~2 m of DNA in each cell is compacted ~10,000-fold into the nucleus. With every division, the telomeres at the 4 chromosome ends shorten — when exhausted, the cell stops dividing (the Hayflick limit). Humans have 46 chromosomes (23 pairs).
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Drag “Condensation level” to watch DNA coil into a chromosome · drag “Division count” (or press ➗) to shorten telomeres · try the Scenarios (karyotype, Down, telomerase…)
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Telomeres shorten with each division (run → Hayflick limit)telomerecondensation