Epigenetics · Cells & Genetics

EPIGENETICS SIMULATION

▸ Wrapping DNA around histone cores → nucleosome chain…

▸ Loading DNMT (methyl) & HAT/HDAC (acetyl) enzymes

▸ Scanning the CpG island at the identity-gene promoter

▸ Linking the switch: chemical marks → chromatin open/close → gene on/off

▸ Ready — Online. ✅

Epigenetic mark levels

🎚️ Cell actively using the gene

methyl (off) vs acetyl (on)

DNA methylation—

Histone acetylation—

Chromatin—

Identity gene—

Expression level—

Protein made—

Note

Epigenetics = a layer of chemical "tags" on DNA & histones that decides which genes are ON/OFF — WITHOUT changing the A–T–G–C sequence. Methylating a CpG island → locks a gene; acetylating histones → opens a gene. These marks are inherited through cell division and are reversible.

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Drag the Methyl/Acetyl sliders to flip the gene switch · pick a scenario (methylation / acetylation / differentiation / reprogramming…) · click "Diagram" to see how chromatin condenses/opens

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Methyl ↔ Acetyl remodel continuously → gene ON/OFF over time methylacetylexpression